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Keywords
Obesity, feeding, reward, leptin, dopamine, behaviour.
Research Interests
Our laboratory studies the neural mechanisms of
food-motivated behaviour. Peripherally-derived metabolic signals
can directly modulate mesolimbic dopamine neurons, an important
component of brain reward circuitry. We are investigating how
hormones such as leptin and insulin act on these systems to
modulate the rewarding effects of foods high in fat and sugar. In
addition, we are interested in the neuroadaptations that occur in
response to high-fat diet and how they may contribute to
over-eating and the development of obesity.
Publications
Publications indexed on PubMed
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